Danny Minkow looks into how the COMET initative is working to developing and apply an agreed-upon set of outcomes measures in medical research. Why is it needed?
This week Robert Kemp grapples with two trials featured in Richard Lehman’s reviews in the BMJ, with a focus on surrogate outcomes.
From Richard’s reviews, we look at a systematic review of management in poorly controlled type 2 diabetes and a study evaluating progress in reducing global childhood mortality.
Surrogate endpoints are like a double edged sword. Even though they do have some benefits on some occasions, they can easily mislead doctors into withdrawing the wrong conclusions. It is, therefore, important to use them with caution.
Nathan has picked out two parts of Richard’s Review for this week which he’s found especially interesting; Niacin, and Sjögren Syndrome.
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