Responder analysis: identifying responders in clinical trials
What is ‘Responder analysis’ and what are the benefits and limitations of this approach? Read more in this blog from Giorgio Karam.
What is ‘Responder analysis’ and what are the benefits and limitations of this approach? Read more in this blog from Giorgio Karam.
Randomized controlled trials (RCTs) can be subject to different kinds of bias. Read about different sources of bias in this blog and how much the magnitude of effect can be changed by the presence of bias.
In this blog, Giorgio Karam examines the evidence on antihypertensive drugs for primary prevention – when do we start treatment?
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A beginner’s guide to standard deviation and standard error: what are they, how are they different and how do you calculate them?
When you see a claim that a treatment or intervention has no effect, it is important to examine the evidence as this may be a misleading statement.
This blog provides a detailed overview of the concept of ‘blinding’ in randomised controlled trials (RCTs). It covers what blinding is, common methods of blinding, why blinding is important, and what researchers might do when blinding is not possible. It also explains the concept of allocation concealment.