This blog introduces you to crossover trials with a clear explanation and example, together with some advantages and limitations of this study design.
This blog introduces you to standardised mortality ratios. What are they, why are they used, how do you calculate them and what are their advantages and limitations.
Following the addition of new features and updates on the Cochrane Library, Hasan provides an illustrative summary of which features he has found most useful.
This article explores circadian rhythm, the prevalence of its disruption in modern society, and its affects on cancer.
This blog presents the abstract of a literature review and critical appraisal on ‘timeliness of the intranasal route of medicines delivery for acute pain in paediatrics’.
This month the media ran several stories about a study exploring the relationship between health and work-life balance. Are we working ourselves towards ill health?
Yousif examines the HIP ATTACK trial, appraises the primary composite endpoint, verifies the assessment and then thinks of ways to interpret the result.
COVID-19 has highlighted the inefficiencies that exist in clinical research, as well as the frailties of the current publishing system. This blog examines two prominent examples from the pandemic.
Our library features links to a range of resources that can help you get to grips with various aspects of evidence-based healthcare. From statistics tutorials to guidance on how to critically appraise a paper. This page is continually updated, so do let us know if you know of resources that are missing.
A patient’s most common reasons for visiting the dentist. While antibiotics are effective for treating numerous infections, how efficacious are they in treatment of toothache?
This blog provides an introduction to critically appraising diagnostic studies. Find out what questions are important to ask as you go through a paper.
Last week the media ran several stories about a research study exploring the link between loneliness, smoking behaviours, and alcohol use. How does the evidence disentangle cause and effect?
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A beginner’s guide to standard deviation and standard error: what are they, how are they different and how do you calculate them?
When you see a claim that a treatment or intervention has no effect, it is important to examine the evidence as this may be a misleading statement.
This blog provides a detailed overview of the concept of ‘blinding’ in randomised controlled trials (RCTs). It covers what blinding is, common methods of blinding, why blinding is important, and what researchers might do when blinding is not possible. It also explains the concept of allocation concealment.