Evidence Reviews
Antibiotic resistance
Rosario De Feo explores the scale of the problem of antibiotic resistance, and some possible ongoing solutions.
A network for students interested in evidence-based health care
Rosario De Feo explores the scale of the problem of antibiotic resistance, and some possible ongoing solutions.
How do different countries promote ethical and efficient organ transplantation? This blog series will explore the policy behind the decisions. This is Part 2 of the series.
How do different countries promote ethical and efficient organ transplantation? This blog series will explore the policy behind the decisions. This is Part 1 of the series.
What is memory? This blog outlines the main types of memory, how they work together, and why forgetting things may not always be bad!
Every March, Endometriosis Awareness Month takes place across the world. But what exactly is endometriosis and why is it vital to continue the dialogue surrounding it even beyond the month of March?
Can UV nail lamps used for gel manicures cause cancer? In early 2023, this question has been raised in the media. What is the evidence behind the headline?
Neurology and endocrinology are today closer than ever in explaining important clinical processes. This blog from Davide aims to provide an extensive overview of the roles played by brain-derived estrogen in neural function.
Digital medication adherence systems are technology-based solutions that help patients manage their medication regimens and improve their adherence to prescribed treatments.
As seen in a previous blog from Davide, modern neuroscience often interfaces with other medical specialities. In this blog, he provides a summary of new evidence about the potential of a therapeutic strategy born at the crossroad between neurology, immunology and oncology.
Shreya provides background and context on the importance and use of decision‐support tools via mobile devices in primary healthcare settings, whilst also summarizing a 2021 Cochrane review on this topic.
Neuroscience is a complex world, strongly linked to other medical specialties or scientific fields. This article offers an example of how basic research could be fundamental to shape the future of medicine. This is the summary of a systematic review about using particular molecules like microRNAs as new biomarkers, to obtain a more accurate diagnosis in Mild Cognitive Impairment.
With the continued growth of an older population, how can artificial intelligence (AI) help improve safety and the level of care received?
In this blog post, Shreya summarizes a 2022 Cochrane systematic review titled ‘Anticoagulants for people hospitalised with COVID-19’, and provides a background to why this review was necessary.
This blog presents the abstract of a literature review and critical appraisal of paramedics’ assessment of older adults who fall and are referred to community care services.
This blog presents the abstract of a literature review and critical appraisal on the topic of endotracheal intubation in prehospital paramedic practice.
In this blog, Carolina provides her own summary of a 2022 Cochrane Systematic Review, ‘Replacing salt with low‐sodium salt substitutes (LSSS) for cardiovascular health in adults, children and pregnant women’.
The combination of rising antibiotic resistance and fewer new antibiotic approvals highlights the importance of judicial antimicrobial management. Many institutions are implementing antimicrobial stewardship programmes (ASPs) to raise awareness of the importance of antibiotic stewardship.
Understanding the natural history and prognosis of musculoskeletal (MSK) conditions and injuries creates a great foundation when starting clinical rotations as a physical therapy student. In this blog, Chris shares his own evolving document which gathers various papers together in one centralized location to help him (and others) find the natural history and prognosis of most MSK conditions
In this blog, Tessa provides her own summary of a 2018 Cochrane Systematic Review, ‘Visual inspection for diagnosing cutaneous melanoma in adults’.
In this blog, Tessa provides her own summary of a 2015 Cochrane Systematic Review, ‘Safety of topical corticosteroids in pregnancy’.
Shared decision making (SDM) is a collaborative process between physician and patient that is applicable to any clinical decision, whether diagnostic, therapeutic, or preventive in nature. In this blog, Tiffany presents why there is an ethical imperative for SDM to be routinely incorporated into everyday patient care within all healthcare settings.
This blog presents the abstract of a literature review and critical appraisal on the topic of intraosseous vascular access in cardiac arrest.
Searching clinical trial registries is an essential tool to improve the value of systematic reviews. This is a resource review on a paper that describes whether and how this is done in published systematic reviews of pharmacotherapy and assesses their quantitative impact on meta-analysis.
Charlotte and Sophie, final year medical students, discuss a recent Cochrane review assessing the effectiveness of interventions for medical students that aim to improve interpersonal communication in medical consultations.
In this blog, Tessa provides her own summary of a 2019 Cochrane Systematic Review, “Lifestyle changes for treating psoriasis”.
Tessa, a final year medical student at Monash University (Malaysia Campus), provides her own summary of a 2018 Cochrane Systematic Review “Oral isotretinoin for acne”.
Healthcare students are often exposed to significant stressors during their studies and work. Are psychological interventions effective in fostering resilience in this cohort?
This article explores circadian rhythm, the prevalence of its disruption in modern society, and its affects on cancer.
This blog presents the abstract of a literature review and critical appraisal on ‘timeliness of the intranasal route of medicines delivery for acute pain in paediatrics’.
This month the media ran several stories about a study exploring the relationship between health and work-life balance. Are we working ourselves towards ill health?
Yousif examines the HIP ATTACK trial, appraises the primary composite endpoint, verifies the assessment and then thinks of ways to interpret the result.
COVID-19 has highlighted the inefficiencies that exist in clinical research, as well as the frailties of the current publishing system. This blog examines two prominent examples from the pandemic.
A patient’s most common reasons for visiting the dentist. While antibiotics are effective for treating numerous infections, how efficacious are they in treatment of toothache?
Last week the media ran several stories about a research study exploring the link between loneliness, smoking behaviours, and alcohol use. How does the evidence disentangle cause and effect?
This blog presents the abstract of a literature review and critical appraisal on the topic of ‘paramedic decision-making to commence or withhold resuscitation attempts in the absence of a ‘Do Not Attempt Cardiopulmonary Resuscitation (DNACPR) order’.
This blog presents the abstract of a literature review and critical appraisal on the topic of ‘effective management by paramedics when caring for patients requiring end of life decision-making’.
This blog presents the abstract of a literature review and critical appraisal on the topic of ‘prevalence of depression in emergency ambulance staff’.
This blog presents the abstract of a literature review on the topic of ‘Paramedics performance of delivering care in a mental health crisis’.
This blog presents the abstract of a literature review and critical appraisal on the topic of ‘Common themes surrounding the topic of electrocardiogram (ECG) lead placement’.
This blog presents the abstract of a literature review and critical appraisal on the topic of ‘Cardiovascular disease in a shift working population of Paramedics’.
How effective is oil pulling in improving oral health? The Ayurvedic technique of oil pulling has become a popular DIY home remedy, promising to cure a plethora of oral health problems. But pulling out the research behind these claims highlights the lack of evidence.
How effective is food as medicine? In April, the media ran several stories about a research study exploring the link between dietary fibre intake and breast cancer. Let’s try and digest the evidence.
In this blog, Roshan, a final year medical student at Monash University, provides his own summary of a 2018 Cochrane Systematic Review “Antipsychotics for treatment of delirium in hospitalised non-ICU patients”.
How does the literature compare to the actual rehabilitation performed in clinical practice after a meniscal repair?
How does the literature compare to the actual rehabilitation performed in clinical practice after subacromial decompression and rotator cuff repair?
This blog presents the abstract of a literature review and critical appraisal on the topic of ‘Morphine administration for patients suffering an acute Myocardial Infarction’.
This blog presents the abstract of a literature review and critical appraisal on the topic of pre-hospital antibiotics for patients with sepsis.
This blog presents the abstract of a literature review and critical appraisal on the topic of ‘Mental Health Considerations in Older Adults’.Â
This blog presents the abstract of a literature review and critical appraisal on the topic of ‘Fascial iliaca Compartment Blocks for femoral fractures’.
This blog looks at the efficacy and acceptability of benzodiazepines vs placebo in treating panic disorder. It provides a summary of a 2019 Cochrane review, looking at the clinical impact of current evidence.
This blog is a critical appraisal of the following pilot study: Intraexaminer comparison of applied kinesiology manual muscle testing of varying durations.
This blog is a critical appraisal of a randomized controlled trial assessing the timing of hypertonic saline and airways clearance techniques in adults with Cystic Fibrosis (CF) during a pulmonary exacerbation.
This blog is a critical appraisal of a randomized controlled trial assessing the effectiveness of land-based versus water-based rehabilitation following total knee replacement.
Is Family Therapy effective in the treatment of Anorexia Nervosa? Emily summarises a recent Cochrane Review in this blog and examines the evidence.
This blog is a critical appraisal of a randomized controlled trial assessing the effectiveness of in-hospital physiotherapy for improving physical activity level after lung cancer surgery.
This blog is a critical appraisal of a randomized controlled trial assessing the effectiveness of individualized manual therapy, in addition to exercises, for treatment of shoulder impingement.
This blog is a critical appraisal of a randomized controlled trial assessing the effectiveness of preoperative physiotherapy for the prevention of respiratory complications after upper abdominal surgery.
Sophia discusses a recent Cochrane review entitled ‘Inpatient versus outpatient care, partial hospitalisation and waiting list for people with eating disorders’ and considers the implications of the findings.
In this blog, Neelam Khan, a fourth year dental student at the University of Manchester, looks at the latest Cochrane evidence on the full publication of study results initially presented in abstracts and reflects on the implications of the findings.
This blog is a critical appraisal of a randomized controlled trial assessing the effectiveness of balance task-specific training following hip fracture.
This blog is a critical appraisal of a randomized controlled trial, assessing the effectiveness of an early rehabilitation intervention to enhance recovery during hospital admission for an exacerbation of chronic respiratory disease.
In this blog, Lucy discusses a recent Cochrane review which summarises all evidence for interventions relevant to the prevention of preterm birth (PTB) as reported in Cochrane systematic reviews (SRs).
In this blog, Sophia discusses a recent Cochrane review which asked the question: are psychological e-health interventions for children and adolescents with long-term physical conditions effective for reducing depression and anxiety?
In this blog, Giorgio Karam examines the evidence on antihypertensive drugs for primary prevention – when do we start treatment?
This blog is a critical appraisal of a randomized controlled trial assessing core stabilization exercises and routine exercise therapy for management of pain in chronic nonspecific low back pain.
This blog is a critical appraisal of a randomised control trial assessing the effectiveness of aquatic exercise in women with Rheumatoid Arthritis.
This blog is a critical appraisal of a retrospective matched control study assessing the effectiveness of robotic-assisted gait training in stroke rehabilitation.
This blog is a critical appraisal of a randomized controlled trial assessing Acapella vs. PEP mask therapy for children with cystic fibrosis during respiratory exacerbation.
This blog is a critical appraisal of a randomized controlled assessing hydrotherapy versus conventional land-based exercise for the management of patients with osteoarthritis of the knee.
A 2014 Cochrane Review compared the effects of using a manual toothbrush with an electric toothbrush for maintaining oral health. What’s the evidence?
This blog is a critical appraisal of a randomized controlled trial examining the effectiveness of different exercises and stretching physiotherapy on pain and movement in patellofemoral pain syndrome.
Myofascial trigger points (MTrPs) are nodules in a tight band of skeletal muscle which have an exaggerated response to moderate stimuli. These MTrPs are present in patients with myofascial pain syndrome (MPS). This blog critically appraises a randomized controlled trial which assessed the responsiveness of MTrPs to trigger point release massages.
This blog critically appraises a randomized controlled trial which compared spinal mobilization vs conventional physiotherapy in management of chronic low back pain due to disc degeneration.
This blog discusses the impact of humanitarian crises on mental health and provides a summary of a 2018 Cochrane Review which assessed the impact of psychological therapies on the mental health of people affected by these crises.
This blog critically appraises a randomized controlled trial looking at the effectiveness of expiratory muscle training on the pulmonary function of patients with high spinal cord injury.
In addictions research, there’s a big emphasis on events leading up to recovery. But what about after?
In this blog, Sophia discusses the term ‘treatment-resistant depression’ (TRD) and provides a summary of a 2018 Cochrane review which assessed the effectiveness for psychological therapies for adults with TRD.
This blog critically appraises a randomized controlled trial looking at the effectiveness of eccentric exercises in combination with PRP injections versus saline injection.
What is the evidence that having high cholesterol, or high LDL (low-density lipoprotein) levels, increases your chance of getting heart disease?
This blog is a critical appraisal of a randomized control trial which examined the effect of a preoperative exercise intervention on knee pain, functional ability, and quadriceps strength among patients with knee osteoarthritis before and after total knee arthroplasty (TKA) surgery.
This blog is a critical appraisal of a randomized control trial which investigates the effects prehabilitation has on quality of life and functional abilities in patients undergoing total knee or hip replacement.
Much research has looked into the use of exercise for patients receiving cancer treatment, however few studies have focused on palliative care. This blog is a critical appraisal of a randomized controlled trial (RCT) which evaluated the use of a physiotherapy programme to reduce cancer related fatigue in palliative cancer patients.
This blog is a critical appraisal of a randomized control trial (RCT) looking at the effect of Physiotherapy on shoulder function in patients surgically treated for breast cancer.
This blog is a critical appraisal of a randomized control trial (RCT) looking at the effectiveness of acupuncture for low back pain.
This blog is a critical appraisal of a Randomized Controlled Trial (RCT) comparing the effects of general exercise, motor control exercise and spinal manipulative therapy on function and perceived effect of intervention in patients with chronic back pain.
In this blog, Julie Duncan Millar, PhD Student and Physiotherapist, reflects on the difficulties of comparing and sharing upper limb rehabilitation trial data and proposes a condensed toolkit of measures recommended for researchers to use in future trials.
Pain is a recurrent undesirable side effect in orthodontic treatment. This blog by Izabel Oliveira introduces pharmacological and non-pharmacological alternatives for orthodontic pain management.
How accurately have the media reported on the link between dentures and frailty? This blog by Neelam Khan looks at the evidence behind the claim that “Dentures put wearers at risk of malnutrition because they can’t chew healthy food”.
Canada is in the midst of an opioid crisis and prescriptions have something to do with it. The question is, what? Lauren Gorfinkel discusses the need for new research which adequately investigates the ways in which prescription opioids enter and influence the lives of not only those who are prescribed opioids, but those that are not.
Is evidence-based medicine a fairy tale? With this in mind, Foo Wee brings her personal experience into a review of the evidence available for analgesic treatment of G6PD deficient children. This blog won 2nd prize in the recent Cochrane Malaysia blog writing competition.
In this blog, Kamal Pandit discusses the findings of three recent Cochrane reviews which assessed the effectiveness of treatments for Coronary heart disease (CHD). He adds personal experience to provide context to treatment of a condition which is the single leading cause of death globally (WHO 2014).
Alina provides a critical appraisal of the ARTEMIDA trial (2015) that assessed efficacy of Actovegin in poststroke cognitive impairment.
This blog is part of the ‘Understanding Evidence’ series, a collaborative series between Cochrane UK and Students 4 Best Evidence. Selena Ryan-Vig, Cochrane UK’s Knowledge and Engagement Officer, takes a look at Cochrane evidence on cocoa and blood pressure and highlights some important considerations when reading research.
This blog is a critical appraisal of a randomized controlled trial which reported that noninvasive ventilation immediately after extubation improves weaning outcome after acute respiratory failure.
This blog is a critical appraisal of a randomised controlled trial comparing a tailored exercise programme with a general exercise programme for individuals with low back pain and movement control impairment.
This blog is a critical appraisal of a Randomized Controlled Trial (RCT) investigating the influence of strength training on quality of life in ischemic stroke survivors.
This blog is a critical appraisal of the following study: Neuromuscular adaptations to long-term progressive resistance training translates to improved functional capacity for people with multiple sclerosis and is maintained at follow-up.
This blog takes a critical look at a systematic review exploring home-based physiotherapy for chronic obstructive pulmonary disease (COPD).
This blog is a critical appraisal of a randomised control trial comparing aerobic interval training with moderate intensity continuous training as part of treatment for patients with myocardial infarction.
This blog is a critical appraisal of a systematic review exploring the benefits of early mobilisation following hip or knee replacement surgery.
This blog is a critical appraisal of a randomised controlled trial exploring the use of non-invasive ventilation as an adjunct to airway clearance treatments during an acute exacerbation of cystic fibrosis.
This blog takes a critical look at whether using the Wii for balance rehabiliation in patients with acquired brain injury is a safe, effective and feasible intervention.
This blog is a critical appraisal of a randomised control trial investigating the effects of bed exercises following a total hip replacement.
In this blog, two physical therapy students describe the occurrence of sexual dysfunction that can occur as a result of pelvic pain, and then argue for physical therapy (PT) to be the first line of treatment for this issue.
Introducing Cochrane UK’s special blog series #theproblemwithsex, which aims to lift the lid on sex and chronic health conditions, on the lack of good evidence for treatments, challenges around talking about sex, and on what can be done to change things for the better.
This blog is a critical appraisal of a randomized controlled trial investigated investigated whether strengthening the hip and core muscles vs. strengthening knee muscles is more effective for the treatment of patellofemoral (knee) pain.
This blog explores the difficulties that mental healthcare professionals may experience when responding to patients who are victims of human trafficking.
This blog takes a critical look at the use of functional electronic stimulation for children with cerebral palsy.
This is a critical analysis of a preliminary randomized control trial to determine if using the Nintendo Wii FitTM would be beneficial as part of the rehabilitation of strength, movement and function following a total knee replacement.
This blog takes a critical look at a randomized controlled trial evaluating the efficacy of an exercise program for improving functioning & pain in pregnant women suffering from low back pain and pelvic pain (LBPP)
This blog takes a critical look at whether including adding task-related exercises to standard rehabilation after a stroke can improve patients’ functioning and mobility.
This blog is the joint winner of our 2017 student competition to win free registration to the Cochrane UK & Ireland symposium 2017.
This blog is the runner-up of our 2017 student competition to win free registration to the Cochrane UK & Ireland symposium 2017.
This blog is the joint winner of our 2017 student competition to win free registration to the Cochrane UK & Ireland symposium 2017.
Can including a structured warm-up exercise programme within a training schedule lead to fewer lower limb injuries among youth athletes?
This blog takes a critical look at whether acupuncture or physiotherapy (compared to usual care) can lead to improvements in knee pain & functionality in patients awaiting knee replacement surgery.
This blog takes a critical look at a randomised controlled trial which assessed the effectiveness of a physiotherapy-led exercise programme after total hip replacement.
This blog discusses the problem of confirmation bias: our tendency to favour answers that confirm ideas and beliefs that we already have. It also discusses two possible solutions to this problem: 1) referring to systematic reviews, which take account of ALL the available evidence and 2) actively seeking out information which may challenge our preconceptions.
This blog takes a critical look at whether a general or tailored exercise programme for a subgroup of individuals with lower back pain is more effective.
This blog takes a critical look at the use of acupuncture for carpal tunnel syndrome.
This study critically appraises an RCT, looking at whether Spinal Manipulative Therapy (SMT) is more effective in patients with chronic low back pain when it’s applied specifically or non-specifically to the back pain area.
This blog is a critical appraisal of a randomised controlled trial looking at the effects of additional therapy on young children with spastic cerebral palsy.
Do patients who have experienced deep vein thrombosis (DVT) or pulmonary embolism (PE) have better outcomes when they receive bed rest OR when they get out of bed and engage in light activity (e.g. walking, standing or sitting) as soon as possible after treatment? (Also known as ‘early ambulation’)
This blog takes a critical look at a strength-based training programme for young people with Down Syndrome.
This blog takes a critical look at whether circuit training may be a safe alternative to usual physiotherapy for patients who’ve suffered a stroke.
In 2016, the World Health Organization published a new handbook on the classification of tumours of the brain and spinal cord. This blog takes a look at some of the changes in the way we classify tumours, given advancements in molecular testing.
This blog takes a critical look at a study investigating whether more intense therapy following a neurological event (e.g. a stroke or traumatic brain injury) can lead to a reduction in length of stay in a rehabilitation unit.
In this blog, 15 year old Liv, who hopes to be a dental health professional, writes about new Cochrane evidence on whether fluoride mouthrinses can prevent tooth decay in children.
This blog looks at the importance of the use of video games or stimulation games for the use in physiotherapy treatment, in relation to aiding patients with proprioception post stroke. It analyses an article looking at balance training post stroke using the Wii Fit balance board and balance games. Reviewing the article and suggesting whether it is relevant or requires further studies or investigations.
Patellofemoral pain syndrome is a common condition that can be caused by multiple factors and can affect quality of life. Rehabilitation involves strengthening of the quadriceps but there is debate about if treatment should focus on being selective to the vastus medialis component of quadriceps. The following is a critical appraisal of a study which investigates if selective strengthening is more beneficial than general strengthening.
Mechanical neck pain is prevalent in the general population. Adjusting the spine (spinal manipulative therapy) is complex and controversial, largely based on the Chiropractic concept of a joint “subluxation”. This blog is a critical appraisal of a study examining the acute effects of a single and multiple level thoracic manipulation on chronic mechanical neck pain.
This week the media ran multiple stories about a research study that may help us crack the secrets of ageing. Heidi takes a look at these articles to see if humans could be eternally youthful in the near future.
Managing hypertension is complex, involves lifestyle modifications such as physical activity and dietary interventions, as well as drugs. Here, we highlight the evidence from Cochrane about which drug is better as a first-line therapy.
This week the media proclaimed that scientists had made a breakthrough that could ‘halt leukaemia in its tracks’ but what’s the evidence?
There is lack of evidence on acute bronchiectasis regarding the use of airway clearance techniques. What is the impact of evidence gap? And what does current evidence say about the use of ACTs for stable bronchiectasis? Read more to to find out.
According to Scottish arthroplasty project ‘Biennial report 2014’, the number of arthroplasty operations has increased over the past 7 years (7609 hip and 7169 knee arthroplasties were performed in 2013) costing the NHS on average £7000 per patient (Scottish Arthroplasty Project 2014). This blog is a critical appraisal of a study which looked at importance of providing patient-cantered care for your patient right from the initial appointment and the positive effects it can have on patient outcome and cost efficiency.
This article highlights the importance of the results of Cochrane’s new systematic review on the efficacy of Methylphenidate for ADHD in children and adolescents.
Migraines are a burden to those who suffer from them; they can reduce one’s quality of life, decrease one’s ability to function, and even impair one’s performance. The goal of this Cochrane Review was to see if SSRIs and SNRIs were effective in the prevention of migraines.
This week the media picked up on health risks associated with consumption of fizzy drinks – the Scots among us may use the term ‘fizzy juice’; I call it ‘pop’. Perhaps an example of my own personal bias, I thoroughly expected these articles to be riddled with inaccuracies; maybe they would even go so far as to claim a causal link with cancer. Though by no means perfect, I was pleasantly surprised with the content of these pieces, ran by
If you’ve read a newspaper or seen the news over the couple of weeks there’s a good chance you’ll have seen a few pretty terrifying headlines related to Alzheimer’s disease… So can you really catch Alzheimer’s disease from blood transfusions, dental visits or surgery? In short: no. Here’s how we know: 1. This was a very small, observational study 8 patients were studied in a purely observational manner; there was no randomisation, control group or blinding. The data is comprised of
The ‘Health in the Media’ feature is back! Iodine deficiency has been linked to poor thyroid function and weight gain, but did the Daily Mail dish out helpful advice on where to find dietary iodine?
Kendall Jenner is among numerous celebs to attribute their svelte physiques to so-called detox tea – but can tea really help you detox and lose weight?
Currently decisions made on treatment of bronchiectasis are based on guidelines which have a very poor evidence base. Read more to find out!
In this blog, Pishoy discusses how the newest Cochrane review impacts how we treat deep vein thrombosis. Are NOACs the way to go?
Medically unexplained physical symptoms. The notion of physical symptoms having no medical causes is not an old one; when is it really a Somatoform disorder and what is the best treatment? Two new Cochrane reviews help answer the question.
Angel takes a look at the new guide on allergies from Sense About Science.
Deevia critically appraises the latest evidence!
David’s prize winning Prezi looking at the latest Cochrane evidence for stroke treatment.
Check out Emily’s prize winning Prezi looking at the latest Cochrane evidence on thrombolysis for acute ischaemic stroke.
“He was 1 of 2 first-year residents who jumped to their death from buildings in New York city…” Find out here what is happening with mental health of physicians and trainees.
Mental health is one of the biggest causes of disability in the developed world, but lacks parity of esteem or of funding with physical health. Alice Buchan looks at the use of Cochrane evidence in a Department of Health medical report on the subject.
Rich Thorley takes a closer look at the reporting of statistics in a recent story about the health benefits of coffee.
Diagnostic tests can be big business. Angel Wong reports on one case study highlighting how deceptive such tests can be.
They’re doing it in restaurants; in bars; in clubs; they’re even doing it at work. But what does the evidence say about the effects of vaping?
Have you ever sat in on a practice meeting or MDT, gobbling sandwiches and cakes that have appeared as if by magic? Have you scribbled feverishly in a lecture with a handy “free” pen emblazoned with a drug brand or company logo? That lanyard round your neck, what does it say again? A paper by Yeh et al published in PLOS Medicine earlier this year from the USA highlights that medical students are frequently entertained by pharmaceutical company representatives, even
This week Robert Kemp grapples with two trials featured in Richard Lehman’s reviews in the BMJ, with a focus on surrogate outcomes.
From Richard’s Reviews, Pishoy highlights the devastating effects of Ebola from a recent article in the New England Journal of Medicine “Clinical Illness and Outcomes in Patients with Ebola in Sierra Leone” as well as give us a brief overview of the viral disease. Clinical Illness and Outcomes in Patients with Ebola in Sierra Leone What is Ebola? Ebola virus disease (EVD) is an infection illness caused by the infamous Ebola virus. The strain that has been identified in the
This time we’re looking at a couple of pragmatically designed randomised controlled trials examining the role of integrated care programmes in treating COPD.
Publication bias is generally ascribed to failure by researchers to submit studies for publication. This current study aims to further evaluate whether the editorial and peer review process also contributes to publication bias.
From Richard’s reviews, we look at a systematic review of management in poorly controlled type 2 diabetes and a study evaluating progress in reducing global childhood mortality.
Norah goes over a couple of interesting studies that were mentioned in one of Richard Lehman’s review of journals for the BMJ. These studies include a new drug for RSV, some unnecessary and other harmful interventions, and the benefits of public transport.
From Richard’s Reviews, we highlight the importance of constantly rethinking how we manage patients with kidney stones (nephorlithiasis) and heart attacks (myocardial infarctions).
From Richard’s review this week, we look at whether bisphosphonates can prevent breast cancer, and whether bivalirudin is actually any better than good old-fashioned heparin in patients with ACS undergoing percutaneous coronary intervention
From Richards’s Review this week, Pishoy highlights the resurrection of the BCG vaccine and the new gene on the block in the world of breast cancer.
In this blog, Norah uses Richard Lehman’s review of journals for the BMJ to find and summarize the new and interesting publications in medical journals.
Nathan has picked out two parts of Richard’s Review for this week which he’s found especially interesting; Niacin, and Sjögren Syndrome.
This week RIchard talked about a hope he has had since long ago concerning a syndrome called Antiphospholipid Syndrome, Yamama tells us more.
As part of our weekly blog on Richard’s Reviews, this week, Pishoy has picked Malaria and Blood Cholesterol.
Antonio takes a detailed look at the latest European Society of Human Reproduction and Embriology guidelines on Endometriosis, from diagnosis to possible treatments.
If you were asked, “What are the most important aspects to clinical trials to remember?” what would you convey to your audience? A project funded by the EU has tried to do just that in an educational video published late last year.
Jeff critically appraises a study looking at interactive gaming.
In one of my clinical placements in a school we had patients that had developmental delays due to a diagnosis of Down syndrome. The school PT and I would perform motor groups with some of these patients and their classmates before working individually with them. I saw many improvements in their gross motor skills as well as their social skills as a result of the motor group sessions. This led me to want to find more research on the benefits of sensorimotor group sessions as a PT intervention.
Have you heard of accelerated recovery programs, but aren’t sure what they are? Or are you wondering if they are safe and effective? If so, check out this post about the use of accelerated recovery programs following knee arthroplasty.
Danny takes a look at Lifestyle Redesign®, a program that promotes mental well-being across community-based living elderly in a cost-effective manner.
Jumper’s knee commonly occurs in athletes involved in jumping sports such as basketball and volleyball. Gradual onset of pain at the front of the knee below the knee cap is the most common complaint of patients experiencing jumper’s knee. Jesse appraises an article looking at possible treatments.
Can interactive gaming help improve balance for patients post-stroke? Article appraisal.
The purpose of this study was to compare traditional warm-up routines during practice and competition in collegiate women’s soccer to the experimental program of neuromuscular strength training.
The effectiveness of using an implanted functional electrical stimulation system in an individual with a cervical incomplete spinal cord injury for walking; address the use for the quality and efficiency of gait.
Study appraisal looking at what shoes the US Marines should buy to prevent injury, but there is little evidence that supports one shoe design over another.
Review of an article that incorporates balance into therapy sessions as a means to improve walking after spinal cord injury.
Adam takes a look at possible treatment for chronic shoulder pain, through critical appraisal of a randomized control trial.
Kristian appraises an article looking at manual therapy for sprained ankles.
Rather than opting for surgical procedures, the literature suggests that conservative treatment such as manual therapy, strengthening, and stretching can provide beneficial relief in pain and stiffness, while improving function. Matt discusses.
Jimmy reviews an article on whether manual physical therapy & exercise is more effective than exercise alone in the management of patients with inversion ankle sprains.
A comparison of training protocols for preventing ACL injuries in female athletes.
Physical therapy student Rachel, reviews an article looking at improving walking ability post-stroke.
A comparison of manual therapy to patellar taping in patients with Patello-Femoral Pain Syndrome (PFPS)
Keely reviews the research and treatments that are being suggested as the best form of treatments for this type of pain in the study by Balthazard et al.
Can the effects of stationary aerobic cycling help improve ambulation distance and speed with patients who experience a stroke?
Travis critically appraises an article on ACL (anterior cruciate ligament) injury in soccer players
An article review about the effects of hip strengthening on treating Patellofemoral Pain Syndrome.
Bryan looks at a study on assessing balance exercise programs for people with Alzheimer’s dementia
A summary of an article investigating whether or not conservative treatment of anterior shoulder instability can help an athlete return to their sport during season, without having to undergo surgery.
Check out how electrical stimulation is being used to help patients walk after a stroke.
Progressive Agility and Trunk Stabilization programs are effective at decreasing return to sport time and the rate of re-injury at 2 weeks and 1 year follow-up, when compared with traditional stretching and strengthening programs.
Improvements in postural instability in patient’s with Parkinson’s Disease
Jackie looks at a study focusing on non-pharmacological treatments for Alzheimer’s Disease symptoms.
Shoulder impingement is a very common and potentially debilitating injury occurring in individuals ranging from young athletes to the elderly. Jeremy looks at study on rehabilitation options.
Amy discusses whether a hippotherapy simulator (therapeutic simulated horseback riding) is effective therapy for children with Cerebral Palsy.
Jessica reviews study looking at variations of therapy for Osteoarthritis of the hip or knee.
Are manual therapy and exercise effective in treating patients with hip and knee OA?
Spasticity (stiffness) is common among patients with spinal cord injuries. This article reviews the effectiveness of body weight supported treadmill training versus tilt table standing to reduce spasticity.
An article review of a study investigating the impact of group aquatic training on gait efficiency in children and adolescents with cerebral palsy.
A critical appraisal of an article investigating the applicability of High Intensity Exercise Training Programs (HIT) on patients in residential care facilities who have moderate-severe physical and cognitive impairments and who are dependent in at least one activity of daily living (ADL).
Is NDT-based therapy & task practice more beneficial in improving walking ability compared to task practice alone in patients post-stroke?
This is an article review of a study done in Germany. The study was a randomized controlled study comparing Nordic walking, LSVT BIG therapy, and a home exercise program for patients with Parkinson’s disease. This study provides great evidence for LSVT BIG therapy. However, there has been limited research done since this study.
A different approach to treating patients with shoulder pain.
At one point in time, I could not tell you what the most fatal and common adult motor neuron disease is. That is because I knew nothing about Amyotrophic Lateral Sclerosis or ALS until just a few years ago.
Kat’s article review discusses Amyotrophic Lateral Sclerosis a progressive disease involving degeneration of motor neurons in the brain and spinal cord and what muscle exercises can help patients.
The number one cause of disability and reason for absentee with industrialized workers is due to low back pain (USA). Hayley discusses possible interventions…
Pulsatile lavage is typically used in wounds to clean out)the wound to prevent further infection and allow the healing process to take place appropriately.
Elizabeth discusses treatment for low back pain in dancers, through an article review.
Long before beginning my studies as a physical therapy student, I was acutely aware of how much a problem back pain could be…
A quicker fix for acute ankle sprains
Children who underwent SDR as well as physiotherapy and regular follow-ups by an experienced team showed improved motor function for up to 10 years after surgery. This information is very useful when discussing treatment options for children with spastic diplegia.
Low back pain can be frustrating, debilitating, and just plain difficult to treat. Take a look at a research article that examines the effectiveness of manual therapy and active exercise for treatment of low back pain.
Does it really make a difference?
Jennifer takes a look at supported treadmill ambulation for patients with Amyotrophic Lateral Sclerosis (ALS).
Common injury, common treatment. But does it really help?
Take a look at what an enzymatic de-bridging agent has to offer!
How do you treat pelvic pain….
David looks at some of the latest health stories in the media.
Alice takes a look at the evidence behind flight socks and other aspects of travel health.
An apple a day may not be enough to keep the doctor away, but half an hour of exercise really could. Find out why not enough is done to promote exercise as medicine despite the evidence.
Abu discusses the evidence behind hypnosis.
Whether you couldn’t get enough of the rolling coverage of the royal birth, or couldn’t wait for it to be over, I have here for you a roundup of some of the recent systematic reviews and evidence related to pregnancy and childbirth (royal or otherwise).
David writes about the UK Government’s recent plans to introduce health checks.
David takes a look at health in the media. This week from America, when he’s meant to be on his holidays.
“Preventive interventions for postnatal psychosis” is a systematic review published in the Cochrane Database of Systematic Reviews in 2013. It aimed to investigate the best available evidence on interventions for preventing Postnatal Psychosis derived from all relevant randomized controlled trials.
Alice has revisited the cord clamping review, she blogged about a couple of months ago…
David takes a look at the evidence behind health news in the media. 20th June.
David explains risk and number needed to treat using an article from the New England Journal of Medicine
Want to find out more about treating Chronic Fatigue Syndrome? Here, the PACE trial for CFS is evaluated using the CASP Tools for Randomised Controlled Trials.
Can probiotics prevent diarrhoea? A new Cochrane review says they can. This blog also walks through a few of the features of Cochrane reviews.
David takes a look at the evidence behind the good, bad and ugly of medical news in the media. Week 2- 13th June 2013
David takes a look at the evidence behind the good, bad and ugly of medical news in the media. Week 1-6th June 2013
Actress Angelina Jolie’s decision to undergo Bilateral Prophylactic Mastectomy has created a media buzz over the past few days. But is there evidence that supports this decision?
The 2007 NICE guidelines recommend that the umbilical cord be cut very soon after birth. However, in the face of evidence in favour of delayed cord clamping, these guidelines may soon be changing.
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Another 20 minute tutorial from Tim.
The nuts and bolts 20 minute tutorial from Tim.
This new webpage from Cochrane UK is aimed at students of all ages. What is evidence-based practice? What is ‘best available research evidence’? Which resources will help you understand evidence and evidence-based practice, and search for evidence?